Efficient synthesis of novel 3-substituted thiopyran-4-ones
Efficient synthesis of novel 3-substituted thiopyran-4-ones
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DOI：
10.1055/s-2007-990806
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发表时间：
2007-11-02
影响因子：
2.6
通讯作者：
Khavasi, Hamidreza
中科院分区：
文献类型：
--
作者：
Abaee, M. Saeed;Mojtahedi, Mohammad M.;Khavasi, Hamidreza
以溴化镁、乙醚和三乙胺为原料，在温和的条件下，通过各种芳香醛与二氢噻喃-4-酮衍生物的羟醛缩合反应，首次合成了几种3-取代噻喃-4-酮。通过光谱和X射线衍射对产物进行了表征。
Synthesis of several 3-substituted thiopyran-4-ones is reported for the first time via aldol condensation of various aromatic aldehydes with dihydrothiopyran-4-one derivatives under very mild conditions using magnesium bromide diethyl etherate and triethylamine. The products were characterized based on spectroscopic and X-ray diffraction experiments.