ISOLATION AND STRUCTURE OF FLUTIMIDE, A NOVEL ENDONUCLEASE INHIBITOR OF INFLUENZA-VIRUS

ISOLATION AND STRUCTURE OF FLUTIMIDE, A NOVEL ENDONUCLEASE INHIBITOR OF INFLUENZA-VIRUS
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DOI:
10.1016/0040-4039(95)00213-v
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发表时间:
1995-03-20
影响因子:
1.8
通讯作者:
SINGH, SB
SINGH, SB
中科院分区:
化学4区
文献类型:
--
作者:
HENSENS, OD;GOETZ, MA;SINGH, SB

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报道了从一新种密孢Delitschia confertaspora中分离得到的荧光转录酶抑制剂氟替米特(I)的结构鉴定。新的天然产物的特征在于N-羟基酰亚胺和环外烯胺官能团。
The isolation and structure elucidation of flutimide (I), an inhibitor of flutranscription endonuclease from Delitschia confertaspora, a new species, is reported. The novel natural product is characterized by N-hydroxyimide and exocyclic enamine functionalities.