Insights into the mechanism of electron transfer and sodium translocation of the Na(+)-pumping NADH:quinone oxidoreductase.

Insights into the mechanism of electron transfer and sodium translocation of the Na(+)-pumping NADH:quinone oxidoreductase.
复制标题

DOI:
10.1016/j.bbabio.2012.03.017
复制
发表时间:
2012-10
期刊:
Biochimica et biophysica acta
影响因子:
--
通讯作者:
Barquera B
Barquera B
中科院分区:
其他
文献类型:
--
作者:
Juárez O;Barquera B

文献摘要

参考文献

被引文献

相似文献

Na+-NQR是一种独特的能量转换复合物,广泛分布于海洋和病原细菌中。它将 NADH 氧化和醌还原产生的能量转化为电化学 Na+ 梯度,为电池提供能量。 Na+-NQR 与任何其他呼吸蛋白均不同源,但与 RNF 复合物密切相关。在这篇综述中,我们提出 Na+-NQR 中的钠泵通过一种新机制与氧化还原反应耦合,该机制在多个位点运行,是间接的,并由蛋白质构象变化介导。
Na+-NQR is a unique energy-transducing complex, widely distributed among marine and pathogenic bacteria. It converts the energy from the oxidation of NADH and the reduction of quinone into an electrochemical Na+-gradient that can provide energy for the cell. Na+-NQR is not homologous to any other respiratory protein but is closely related to the RNF complex. In this review we propose that sodium pumping in Na+-NQR is coupled to the redox reactions by a novel mechanism, which operates at multiple sites, is indirect and mediated by conformational changes of the protein.
DOI: 10.1007/bf00416604
发表时间: 1989-04-01
影响因子: 2.8
作者:
DIMROTH, P;THOMER, A
通讯作者: THOMER, A
DOI: 10.1016/s0005-2728(02)00342-0
发表时间: 2002-12-02
影响因子: 4.3
作者:
Bogachev, AV;Bertsova, YV;Verkhovsky, MI
通讯作者: Verkhovsky, MI
DOI: 10.1021/bi800920j
发表时间: 2008-10-28
期刊: BIOCHEMISTRY
影响因子: 2.9
作者:
Backiel, Julianne;Juarez, Oscar;Zagorevski, Dmitri V.;Wang, Zhenyu;Nilges, Mark J.;Barquera, Blanca
通讯作者: Barquera, Blanca
DOI: 10.1021/bi048689y
发表时间: 2004-09-28
期刊: BIOCHEMISTRY
影响因子: 2.9
作者:
Barquera, B;Nilges, MJ;Gennis, RB
通讯作者: Gennis, RB
DOI: 10.1021/bi011873o
发表时间: 2002-03-19
期刊: BIOCHEMISTRY
影响因子: 2.9
作者:
Barquera, B;Hellwig, P;Gennis, RB
通讯作者: Gennis, RB