Design and Testing of Stimulation and Myoelectric Recording Modules in an Implanted Distributed Neuroprosthetic System.
Design and Testing of Stimulation and Myoelectric Recording Modules in an Implanted Distributed Neuroprosthetic System.
复制标题
植入分布式神经假体系统中刺激和肌电记录模块的设计和测试。
DOI：
10.1109/tbcas.2021.3066838
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发表时间：
2021-04
影响因子：
5.1
通讯作者：
Smith B
中科院分区：
文献类型：
--
作者：
Makowski N;Campean A;Lambrecht J;Buckett J;Coburn J;Hart R;Miller M;Montague F;Crish T;Fu M;Kilgore K;Peckham PH;Smith B
植入式运动神经假体可以通过以协调的模式电激活瘫痪的肌肉来恢复神经残疾者的功能。神经假体系统的典型设计依赖于单个多用途设备，但这限制了实际可实现的刺激和传感器通道的数量。为了解决这一限制，开发了一种模块化神经假体，即“网络化神经假体”（NNP）。NNP系统是第一个完全植入的模块化神经假体，包括植入所有电源、信号处理、生物电位信号记录和刺激组件。本文介绍了刺激和记录模块的设计，台架测试，以验证刺激输出和适当的过滤和记录，并验证组件的功能正常，而实施的人脊髓损伤。系统测试的结果表明，NNP功能正常，能够产生刺激脉冲并记录肌电、温度和加速度计信号。基于NNP系统的成功设计、制造和测试，预期可用于多种临床应用。
Implantable motor neuroprostheses can restore functionality to individuals with neurological disabilities by electrically activating paralyzed muscles in coordinated patterns. The typical design of neuroprosthetic systems relies on a single multi-use device, but this limits the number of stimulus and sensor channels that can be practically implemented. To address this limitation, a modular neuroprosthesis, the “Networked Neuroprothesis” (NNP), was developed. The NNP system is the first fully implanted modular neuroprosthesis that includes implantation of all power, signal processing, biopotential signal recording, and stimulating components. This paper describes the design of stimulation and recording modules, bench testing to verify stimulus outputs and appropriate filtering and recording, and validation that the components function properly while implemented in persons with spinal cord injury. The results of system testing demonstrated that the NNP was functional and capable of generating stimulus pulses and recording myoelectric, temperature, and accelerometer signals. Based on the successful design, manufacturing, and testing of the NNP System, multiple clinical applications are anticipated.