Verbal and figural fluency in patients with mass lesions of the left or right frontal lobes.
Verbal and figural fluency in patients with mass lesions of the left or right frontal lobes.
复制标题
左额叶或右额叶肿块病变患者的言语和图形流畅性。
DOI：
10.1076/jcen.21.2.229.928
复制
发表时间：
1999
影响因子：
2.2
通讯作者：
Klaus W. Lange
中科院分区：
文献类型：
--
作者：
O. Tucha;C. Smely;Klaus W. Lange
言语和图形流畅性受损已被证明与额叶功能障碍有关。 Jones-Gotman 和 Milner (1977) 在一小部分患有左半球或右半球额叶损伤的患者中证明了语言和非语言流畅性之间的双重分离。本研究检查了 25 名健康参与者和 95 名左额叶或右额叶有肿块病变的患者的语言和非语言流畅性。与健康参与者相比，左半球额叶病变患者的言语流畅性有所下降。右侧病变的患者与对照组或左侧额叶肿块病变的患者没有差异。在图形流畅性任务中，各组的表现没有差异。研究结果表明，左额叶病变患者比健康参与者产生的单词更少，这表明左额叶病变与言语流畅性下降之间存在关联。结果不支持言语/图形流畅性与额叶内病变侧面之间双重分离的假设。
Impaired verbal and figural fluency has been shown to be associated with frontal lobe dysfunction. Jones-Gotman and Milner (1977) demonstrated a double dissociation between verbal and nonverbal fluency in a small sample of patients with frontal lesions of the left or right hemisphere. The present study has examined verbal and nonverbal fluency in 25 healthy participants and 95 patients with mass lesions of the left or right frontal lobes. In comparison with healthy participants, verbal fluency was reduced in patients with frontal lesions of the left hemisphere. Patients with right-sided lesions did not differ from either the control group or from the patients with left-sided frontal mass lesions. In the figural fluency task, the performance of the groups did not differ. The finding that patients with left frontal lesions produced fewer words than healthy participants suggests an association between left frontal lobe pathology and reduced verbal fluency. The results do not support the hypothesis of a double dissociation between verbal/figural fluency and the side of lesion within the frontal lobes.