Does ICU-acquired paresis lengthen weaning from mechanical ventilation?
Does ICU-acquired paresis lengthen weaning from mechanical ventilation?
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DOI：
10.1007/s00134-004-2174-z
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发表时间：
2004-06-01
影响因子：
38.9
通讯作者：
Brochard, L
中科院分区：
文献类型：
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作者：
De Jonghe, B;Bastuji-Garin, S;Brochard, L
Objective.确定ICU获得性轻瘫（ICUAP）是否是延长撤机的独立危险因素。设计第二项研究是一项前瞻性队列研究，包括95例入组ICUAP发病率和风险因素研究的患者。设置.四家医院的三个内科和两个外科ICU。患者和参与者。95例无既存神经肌肉疾病的患者在机械通气≥ 7天后从危重病急性期恢复。干预。一个也没有。测量和结果。脱离机械通气的持续时间定义为从苏醒（第1天）到成功脱离之间的机械通气持续时间。使用医学研究理事会（MRC）评分在觉醒后第7天评估肌肉力量。MRC患者
Objective. To determine whether ICU-acquired paresis (ICUAP) is an independent risk factor of prolonged weaning. Design. Second study of a prospective cohort of 95 patients who were enrolled in an incidence and risk factor study of ICUAP. Setting. Three medical and two surgical ICUs in four hospitals. Patients and participants. Ninety-five patients without pre-existing neuromuscular disease recovering from the acute phase of critical illness after greater than or equal to7 days of mechanical ventilation. Interventions. None. Measurements and results. Duration of weaning from mechanical ventilation was defined as the duration of mechanical ventilation between awakening (day 1) and successful weaning. Muscle strength was evaluated at day 7 after awakening using the Medical Research Council (MRC) score. Patients with an MRC