Principles of cargo attachment to cytoplasmic motor proteins
Principles of cargo attachment to cytoplasmic motor proteins
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DOI：
10.1016/s0955-0674(01)00295-2
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发表时间：
2002-02-01
影响因子：
7.5
通讯作者：
Goldstein, LSB
中科院分区：
文献类型：
--
作者：
Kamal, A;Goldstein, LSB
细胞骨架运动蛋白附着在载货囊泡上对于细胞膜内运输途径的有效运输至关重要。最近的研究已经确定了特定的动力蛋白结合蛋白和动力蛋白结合蛋白，它们可以作为各自马达的膜相关“受体”蛋白。关于运动蛋白的载货结合结构域以及运动蛋白与载货结合的调控，也出现了新的见解。
The attachment of cytoskeletal motor proteins to cargo-laden vesicles is crucial for efficient transport in intracellular membrane trafficking pathways. Recent studies have identified specific kinesin-binding and dynein-binding proteins that could serve as membrane-associated 'receptor' proteins for the respective motors. New insights have also emerged about the cargo-binding domains of the motor proteins, and the regulation of motor binding to cargoes.