The association between protein-energy malnutrition, malaria morbidity and all-cause mortality in West African children
The association between protein-energy malnutrition, malaria morbidity and all-cause mortality in West African children
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DOI：
10.1046/j.1365-3156.2003.01043.x
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发表时间：
2003-06-01
影响因子：
3.3
通讯作者：
Becher, H
中科院分区：
文献类型：
--
作者：
Müller, O;Garenne, M;Becher, H
疟疾和蛋白质能量营养不良 (PEM) 在撒哈拉以南非洲地区的幼儿中非常普遍，并且 PEM 与疟疾之间的关系仍然存在争议。我们分析了布基纳法索疟疾肆虐农村地区 709 名 6-30 个月大儿童的 PEM、疟疾发病率和全因死亡率之间的关联。通过纵向疟疾监测并辅以三项横断面临床调查，对 1999 年疟疾主要传播期（6 月至 12 月）的研究儿童进行了跟踪。 PEM 与疟疾发病率之间没有关联，但营养不良儿童的死亡风险比非营养不良儿童高两倍多。
Both malaria and protein-energy malnutrition (PEM) are highly prevalent in young children of sub-Saharan Africa, and the association between PEM and malaria continues to be discussed controversially. We analysed the association between PEM, malaria morbidity and all-cause mortality in a cohort of 709 children aged 6-30 months in a malaria holoendemic rural area of Burkina Faso. Study children were followed over the main malaria transmission period (June-December) in 1999 through longitudinal malaria surveillance complemented by three cross-sectional clinical surveys. There was no association between PEM and malaria morbidity, but malnourished children had a more than two-fold higher risk of dying than non-malnourished children.