Implementation of a hepatitis A/B vaccination program using an accelerated schedule among high-risk inmates, Los Angeles County Jail, 2007-2010
Implementation of a hepatitis A/B vaccination program using an accelerated schedule among high-risk inmates, Los Angeles County Jail, 2007-2010
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DOI：
10.1016/j.vaccine.2012.09.006
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发表时间：
2012-11-06
期刊：
影响因子：
5.5
通讯作者：
Malek, Mark
中科院分区：
文献类型：
--
作者：
Costumbrado, John;Stirland, Ali;Malek, Mark
背景资料：疾病控制和预防中心建议为男男性行为者（MSM）和注射吸毒者接种甲型肝炎和B肝炎疫苗。这项研究是美国监狱中肝炎疫苗接种计划的第一份报告，该计划使用加速计划进行联合疫苗接种。洛杉矶县拥有全国最大的监狱系统，男子中央监狱（MCJ）是该系统中最大的设施。MCJ包括一个自我认定的男男性行为者的单位，每年大约有2 700名囚犯被安置在这里。方法和调查结果：从2007年8月开始，向所有被安置在这个特殊单位的囚犯提供甲型和B型肝炎联合疫苗。截至2010年6月，使用加速时间表（0天、7天、21-30天、12个月加强剂），共向1 633名囚犯注射了3 931剂。其中，77%接受了2剂，58%接受了3剂，11%接受了加强剂。在这个单位的性传播感染筛查阳性的囚犯是1.3倍更有可能接种疫苗（95%CI 1.2-1.4）相比，其他人在同一个住房单元谁筛选negative.Conclusions：肝炎疫苗接种计划可以成功地实施在城市监狱中的一个极高风险的人群使用加速，结合甲型/B型肝炎疫苗。我们的研究可能是其他为被监禁人群接种疫苗的项目的有用模式。(C)2012爱思唯尔有限公司保留所有权利。
Background: The Centers for Disease Control and Prevention recommend vaccination for men who have sex with men (MSM) and injection drug users against hepatitis A and B. This study is the first report of a hepatitis vaccination program in a United States jail with a combined vaccine using an accelerated schedule. Los Angeles County has the largest jail system in the nation and Men's Central Jail (MCJ) is the largest facility within that system. MCJ includes a unit for self-identified MSM, where approximately 2700 inmates are housed per year.Methods and findings: Starting in August 2007, a combined hepatitis A and B vaccine was offered to all inmates housed in this special unit. Using an accelerated schedule (0-, 7-, 21-30 days, 12-month booster), a total of 3931 doses were administered to 1633 inmates as of June 2010. Of those, 77% received 2 doses, 58% received 3 doses, and 11% received the booster dose. Inmates who screened positive for a sexually transmitted infection in this unit were 1.3 times more likely to be vaccinated (95% CI 1.2-1.4) compared to others in the same housing unit who screened negative.Conclusions: Hepatitis vaccination initiatives can be successfully implemented in an urban jail among an extremely high-risk population using the accelerated, combined hepatitis A/B vaccine. Ours may be a useful model for other programs to vaccinate incarcerated populations. (C) 2012 Elsevier Ltd. All rights reserved.