Maternal nutritional status, diabetes and risk of macrosomia among Native Canadian women
Maternal nutritional status, diabetes and risk of macrosomia among Native Canadian women
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DOI：
10.1016/s0378-3782(97)00074-1
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发表时间：
1998-02-27
影响因子：
2.5
通讯作者：
Sugamori, ME
中科院分区：
文献类型：
--
作者：
Caulfield, LE;Harris, SB;Sugamori, ME
1990-1993年，采用多变量方法对来自加拿大安大略苏族瞭望台区的741名加拿大土著妇女的单胎分娩中巨大儿（出生体重> 4000 g）的危险因素进行了鉴定。平均出生体重为3691 ± 577 g，29.2%的婴儿出生时体重超过4000 g。巨大儿出生在较晚的胎龄，更有可能是男性。分娩巨大儿的妇女身高较高，怀孕时身体质量指数（BMI）较高，怀孕期间体重增加较多，但吸烟的可能性较小。她们更有可能曾产过巨大儿，并患有妊娠糖尿病（GDM）。巨大儿的风险与母亲血糖水平有关;有糖尿病的妇女风险最大，其次是GDM A（2）（空腹血糖大于或等于6 mmol/l）。GDM A（1）女性（空腹血糖
Multivariate methods were used to identify risk factors for macrosomia (birth weight > 4000 g) among 741 singleton births to Native Canadian women from Sioux Lookout Zone, Ontario, Canada, in 1990-1993. The average birth weight was 3691 +/- 577 g, and 29.2% of infants weighed more than 4000 g at birth. Macrosomic infants were born at later gestational ages and were more likely to be male. Women delivering macrosomic infants were taller, entered pregnancy with higher body mass indexes (BMI) and gained more weight during pregnancy, but were less likely to smoke cigarettes. They were more likely to have previously delivered a macrosomic infant and to have had gestational diabetes mellitus (GDM). Risk of macrosomia was associated with maternal glycemic status; women with pre-existing diabetes were at greatest risk, followed by those with GDM A(2) (fasting glucose greater than or equal to 6 mmol/l). Women with GDM A(1) (fasting glucose