FORCES BETWEEN SURFACES OF BLOCK COPOLYMERS ADSORBED ON MICA
FORCES BETWEEN SURFACES OF BLOCK COPOLYMERS ADSORBED ON MICA
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DOI：
10.1021/ja00271a014
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发表时间：
1986-05-28
影响因子：
15
通讯作者：
TIRRELL, M
中科院分区：
文献类型：
--
作者：
HADZIIOANNOU, G;PATEL, S;TIRRELL, M
尽管尼龙胶囊膜只是半透性的，但用脂质双层塞住的胶囊可以通过外部电场可逆地调节渗透性。由电击穿引起的瞬时孔在软化双层中可逆地产生很长的持续时间（3-5分钟），并且对染料渗透具有选择性。然而，脂质体膜很难实现可逆渗透控制并长时间形成瞬时孔，因为它们在电场作用下很容易损坏或相互融合。相反，双层栓塞胶囊膜不会被连续和间歇电场损坏，因为脂质双层由物理坚固的尼龙胶囊壁支撑。由电场引起的信号接收渗透性控制是可重复的并且对于其中神经电脉冲启动化学中间体的快速释放的突触系统模型是有用的。登记号1, 97732-71-3； 2、99646-32-9； 3、130-14-3； 4、1655-29-4； 5、5182-30-9； 6、59572-10-0；二-4-ASP，101630-71-1； 2CI2N+ 2C „3282-73-3; 2C14N+ 2C1, 68105-02-2; 2C16N+ 2C „70755-47-4; 2C18N+-2Ch 3700-67-2; 2C12PCV, 45300-74-1; 2CI6PC, 18545-88-5；C12-BB-C4-N\101630-72-2；C12-偶氮-C4-N+，101630-73-3；氯化钠，7647-14-5；
Although nyloncapsule membranes were simply semipermeable, the capsule corked with lipid bilayerscould reversibly regulate the permeability by the external electric field. The transient pores induced by an electrical breakdown are reversibly generated for a long duration (3-5 min) in the corking bilayers and have a selectivity for the dye permeation. It is difficult, however, for liposomal membranes to realize the reversible permeation control and form transient pores for any long duration, because they are easily damaged or fused each other under the electric field. On the contrary, the bilayer-corked capsule membrane is not damaged by the continuous and intermittent electric field, because lipid bilayers are supported by the physically strong nylon capsule wall. The signal receptive permeability control induced by the electric field is reproducible and useful for a model of the synaptic systems in which a nerve electrical impulse initiates the rapid release of a chemical intermediary.Registry No. 1, 97732-71-3; 2, 99646-32-9; 3, 130-14-3; 4, 1655-29-4; 5, 5182-30-9; 6, 59572-10-0; di-4-ASP, 101630-71-1; 2CI2N+ 2C „3282-73-3; 2C14N+ 2C1, 68105-02-2; 2C16N+ 2C „70755-47-4; 2C18N+-2Ch 3700-67-2; 2C12PCV, 45300-74-1; 2CI6PC, 18545-88-5; C12-BB-C4-N\101630-72-2; C12-Azo-C4-N+, 101630-73-3; NaCl, 7647-14-5;