Epidemiological analysis of 133 malaria cases in Shanxian County, Shandong Province, China
Epidemiological analysis of 133 malaria cases in Shanxian County, Shandong Province, China
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山东省单县133例疟疾病例流行病学分析
DOI：
10.1016/j.apjtm.2017.08.004
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发表时间：
2017-08-01
影响因子：
3.1
通讯作者：
Gong, Mao-Qing
中科院分区：
文献类型：
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作者：
Shi, Qi-Qi;Cheng, Peng;Gong, Mao-Qing
目的：对山县2002~2016年疟疾疫情变化进行分析。方法：对山县2002~2016年疫情进行回顾性调查，利用网络报告系统收集资料，分析疫情特征。所有个案信息均来自当地山东省寄生虫病研究所组织的村疟疾服务人员。结果：山县共确诊疟疾133例，其中本土病例124例(93.2%)，输入性病例9例(6.8%)。124例原发疟疾患者感染间日疟原虫。9例确诊输入性病例中，7例感染恶性疟原虫，1例感染卵形疟原虫，1例混合间日疟原虫感染。疟疾病例总数为男性86例(64.7%)，女性47例(35.3%)。患者的年龄从1岁到83岁不等，尽管大多数(64.7%)感染发生在21岁到60岁年龄组。值得注意的是，2006-2011年报告的疟疾病例总数中有117例(98.0%)。6-10月为流行季节，每年7-9月为高峰期。感染者最常见的职业是农民。总体而言，58.1%的病例发生在福冈、黄冈和曹庄3个乡镇。结论：单县当地疟疾发病处于出现-高峰-控制-消除状态。然而，由于从非洲返回的移徙劳工人数众多，输入性病例持续存在，并呈逐年增加的趋势，成为消除疟疾的一个不可忽视的重大障碍。因此，需要消除疟疾重新传入接受疟疾的无疟疾地区的情况，应推动战略与流行病学变化保持一致。
Objective: To conduct an analysis of the epidemiological changes in malaria that have occurred in Shanxian county from 2002 to 2016. Methods: A retrospective study was conducted and data were collected from web-based reporting system to explore the epidemiological characteristics in Shanxian county from 2002 to 2016. All individual case information was obtained from village malaria servicers organized by the local Shandong institute of Parasitic Diseases. Results: A total of 133 cases were identified as malaria in Shanxian county during this period, including 124 indigenous cases (93.2%) and 9 imported cases (6.8%). The 124 indigenous malaria cases were infected with Plasmodium vicar (P. vivax). whereas 7 of the 9 confirmed imported cases were infected with Plasmodium falciparum (P. falciparum), I was infected with Plasmodium ovate (P. male) and 1 patient was infected with P. fidcipanan mixed with P. vivax. The total number of malaria cases included 86 males (64.7%) and 47 females (35.3%). Age of the patients ranged from I to 83 years, although most (64.7%) infections occurred in the 2I-to 60-year-old age group. Remarkably, 117 of the total malaria cases (98.0%) were reported from 2006-2011. The epidemic season was from June to October, with the peak occurring yearly from July to September. The most common occupation of the infected patients was farmer. In total, 58.1% of the cases occurred in 3 townships, namely, Fugang, Huanggang and Caozhuang. Conclusions: In Shanxian county, the local malaria incidence experienced an emerge-peak-control-eliminate status. However, due to the numbers of migrant labourers returning from Africa, imported cases were continuous and presented an increasing annual trend, which became a non-negligible and a significant impediment for malaria elimination. Therefore, the need to eliminate instances of malaria reintroduction to receptive malaria-free areas should drive strategies to align with the epidemiological changes.