Internal models of sensorimotor integration regulate cortical dynamics
Internal models of sensorimotor integration regulate cortical dynamics
复制标题
DOI：
10.1038/s41593-019-0500-6
复制
发表时间：
2019-11-01
影响因子：
25
通讯作者：
Jazayeri, Mehrdad
中科院分区：
文献类型：
--
作者：
Egger, Seth W.;Remington, Evan D.;Jazayeri, Mehrdad
显性运动中的感觉运动控制由三个组成部分构成：控制器、模拟器和状态估计器。我们问，同样的框架是否可以解释在没有运动的情况下对内部状态的控制。最近，有研究表明，大脑通过调整内部的速度指令来控制未来动作的时机。我们训练猴子完成一项新颖的任务，在这项任务中，速度指令必须根据一系列闪光的时间进行动态控制。来自额叶皮质的记录提供了证据，表明大脑在每次闪光后更新内部速度指令，这是基于闪光时间与从模拟运动计划得出的闪光预期时间之间的误差。这些发现表明，对内部状态的认知控制可以按照与运动控制相同的计算原理来理解。
Sensorimotor control during overt movements is characterized in terms of three building blocks: a controller, a simulator and a state estimator. We asked whether the same framework could explain the control of internal states in the absence of movements. Recently, it was shown that the brain controls the timing of future movements by adjusting an internal speed command. We trained monkeys in a novel task in which the speed command had to be dynamically controlled based on the timing of a sequence of flashes. Recordings from the frontal cortex provided evidence that the brain updates the internal speed command after each flash based on the error between the timing of the flash and the anticipated timing of the flash derived from a simulated motor plan. These findings suggest that cognitive control of internal states may be understood in terms of the same computational principles as motor control.