Cu(II)-mediated ortho C-H alkynylation of (hetero)arenes with terminal alkynes.
Cu(II)-mediated ortho C-H alkynylation of (hetero)arenes with terminal alkynes.
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DOI：
10.1021/ja507704b
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发表时间：
2014-08
影响因子：
15
通讯作者：
Ming Shang;Hongli Wang;Shang-Zheng Sun;H. Dai;jin-quan yu
中科院分区：
文献类型：
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作者：
Ming Shang;Hongli Wang;Shang-Zheng Sun;H. Dai;jin-quan yu
采用Cu（II）催化芳烃和杂芳烃与末端炔的邻位炔化反应制备了芳基炔。带有不同取代基的各种芳烃和末端炔与该反应相容，从而为Sonogashira偶联提供了另一种断开。
Cu(II)-promoted ortho alkynylation of arenes and heteroarenes with terminal alkynes has been developed to prepare aryl alkynes. A variety of arenes and terminal alkynes bearing different substituents are compatible with this reaction, thus providing an alternative disconnection to Sonogashira coupling.