Autism and sleep disorders.
Autism and sleep disorders.
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DOI：
10.4103/1817-1745.174438
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发表时间：
2015-10
影响因子：
0.5
通讯作者：
Hegde AU
中科院分区：
文献类型：
--
作者：
Devnani PA;Hegde AU
“自闭症谱系障碍”（ASDs）是一种神经发育障碍，其特征是在互惠的社会互动和沟通方面持续受损。ASD的睡眠问题是影响社会交往、日常生活、学习成绩的一个突出特征，并与母亲压力增加和父母睡眠中断有关。对ASD儿童的多导睡眠图研究显示，他们的大部分异常与快速眼动（REM）睡眠有关，包括睡眠数量减少、无分化睡眠增加、眼动未成熟地组织成离散的爆发、卧床时间减少、总睡眠时间减少、快速眼动睡眠潜伏期减少、第一阶段睡眠比例增加。实施非药物治疗措施，如就寝时间和睡眠明智的方法是行为管理的主要内容。治疗策略和有限的药物治疗可以帮助改善ASD儿童的生活质量，并对家庭产生有益的影响。PubMed检索1995年1月至2015年1月的英文文章。以下关键词：自闭症谱系障碍，睡眠障碍与自闭症，快速眼动睡眠与自闭症，认知行为疗法，睡眠方法，褪黑激素与ASD。仅纳入报告与上述问题相关的原始数据的文章。
“Autism Spectrum Disorders” (ASDs) are neurodevelopment disorders and are characterized by persistent impairments in reciprocal social interaction and communication. Sleep problems in ASD, are a prominent feature that have an impact on social interaction, day to day life, academic achievement, and have been correlated with increased maternal stress and parental sleep disruption. Polysomnography studies of ASD children showed most of their abnormalities related to rapid eye movement (REM) sleep which included decreased quantity, increased undifferentiated sleep, immature organization of eye movements into discrete bursts, decreased time in bed, total sleep time, REM sleep latency, and increased proportion of stage 1 sleep. Implementation of nonpharmacotherapeutic measures such as bedtime routines and sleep-wise approach is the mainstay of behavioral management. Treatment strategies along with limited regulated pharmacotherapy can help improve the quality of life in ASD children and have a beneficial impact on the family. PubMed search was performed for English language articles from January 1995 to January 2015. Following key words: Autism spectrum disorder, sleep disorders and autism, REM sleep and autism, cognitive behavioral therapy, sleep-wise approach, melatonin and ASD were used. Only articles reporting primary data relevant to the above questions were included.