Estimation of relative risk from vital data: smoking and cancers of the lung and bladder.

Estimation of relative risk from vital data: smoking and cancers of the lung and bladder.
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根据重要数据估计相对风险:吸烟与肺癌和膀胱癌。

DOI:
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发表时间:
1979
期刊:
Journal of the National Cancer Institute
影响因子:
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通讯作者:
S. Moolgavkar
S. Moolgavkar
中科院分区:
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文献类型:
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作者:
R. Stevens;S. Moolgavkar

文献摘要

被引文献

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分析了英格兰和威尔士肺癌和膀胱癌的死亡率数据。通过使用关于香烟消费的详细信息,非线性最小二乘分析表明,男性和女性在这些癌症发病率方面的差异可以根据吸烟习惯的差异来解释。此外,还获得了吸烟所致相对风险的估计值。吸烟146,000支(相当于20支/天,20年)的相对风险为肺癌4.3,膀胱癌2.9。这些估计与其他类型的流行病学研究所获得的结果一致。
Mortality data from cancers of the lung and bladder in England and Wales were analyzed. With the use of detailed information on cigarette consumption, a nonlinear least-squares analysis showed that the differences between males and females in the rates of these cancers could be explained on the basis of differences in smoking habits. Furthermore, estimates of the relative risk due to smoking were obtained. The relative risks of smoking 146,000 cigarettes (equivalent to 20 cigarettes/day for 20 yr) were 4.3 for lung cancer and 2.9 for bladder cancer. These estimates agree with those obtained by other types of epidemiologic studies.