An in vivo 31P NMR study of cerebral hypoxic hypoxia in rats.
An in vivo 31P NMR study of cerebral hypoxic hypoxia in rats.
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大鼠脑缺氧缺氧的体内 31P NMR 研究。
DOI：
10.1002/mrm.1910030414
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发表时间：
1986
影响因子：
3.3
通讯作者：
James,TL
中科院分区：
文献类型：
--
作者：
Litt,L;González-Méndez,R;Weinstein,PR;Severinghaus,JW;Hamilton,WK;Shuleshko,J;Murphy-Boesch,J;James,TL
在5只麻醉大鼠中，20分钟的低氧可可逆地降低脑PCr和pH，而ATP保持恒定。恢复供氧后，代谢和神经功能完全恢复。仔细控制生理参数，导致每只动物的代谢物变化相同，误差范围内。出版社：Academic Press，Inc.
Twenty minutes of hypoxic hypoxia in five anesthetized rats reversibly reduced cerebral PCr and pH while ATP stayed constant. Complete metabolic and neurologic recovery occurred after oxygen was restored. Careful control of physiological parameters resulted in metabolite changes that were the same, within errors, in each animal. © 1986 Academic Press, Inc.