Acute transplant rejection induced by blood transfusion reaction to the Kidd blood group system
Acute transplant rejection induced by blood transfusion reaction to the Kidd blood group system
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DOI：
10.1093/ndt/gfh333
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发表时间：
2004-09-01
影响因子：
6.1
通讯作者：
Burns, A
中科院分区：
文献类型：
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作者：
Holt, S;Donaldson, H;Burns, A
许多肾移植中心现在试图避免在肾移植前输血，以避免由于针对受污染的白细胞上通常存在的供体抗原产生抗体而产生的同种免疫。手术后或围手术期的输血通常不被认为存在问题，因为患者的免疫功能严重受抑。我们报告了一例罕见的输血反应，我们认为这可能引发了肾移植的严重血管排斥反应，可能是由KIDD血型抗原介导的。
Many renal transplant centres now try to avoid blood transfusion prior to renal transplantation, to avoid alloimmunization due to antibody production against donor antigens usually present on contaminating white cells. Post- or peri-operative transfusions are usually not considered to present problems, since the patient is heavily immunosuppressed. We present a patient who suffered a rare transfusion reaction, that we believe may have initiated a severe vascular rejection of a kidney transplant, probably mediated by Kidd blood group antigens.