Significance of HbA1c Test in Diagnosis and Prognosis of Diabetic Patients
Significance of HbA1c Test in Diagnosis and Prognosis of Diabetic Patients
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DOI：
10.4137/bmimi.s38440
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发表时间：
2016-01-01
影响因子：
3.8
通讯作者：
Sakharkar, Meena K.
中科院分区：
文献类型：
--
作者：
Sherwani, Shariq I.;Khan, Haseeb A.;Sakharkar, Meena K.
糖尿病是一种全球流行病，在发展中国家和发达国家的发病率都在迅速增加。美国糖尿病协会推荐糖化血红蛋白（HbA1c）作为诊断糖尿病的空腹血糖的可能替代品。HbA1c是长期血糖控制的重要指标，能够反映前两到三个月的累积血糖史。HbA 1c不仅提供了慢性高血糖的可靠测量指标，而且与长期糖尿病并发症的风险密切相关。HbA1c升高也被认为是有或无糖尿病受试者中冠心病和卒中的独立风险因素。由一个单一的HbA1c测试提供的有价值的信息，使其成为糖尿病诊断和预后的可靠生物标志物。本文就HbA1c在糖尿病诊断和预后中的作用作一综述。
Diabetes is a global endemic with rapidly increasing prevalence in both developing and developed countries. The American Diabetes Association has recommended glycated hemoglobin (HbA1c) as a possible substitute to fasting blood glucose for diagnosis of diabetes. HbA1c is an important indicator of long-term glycemic control with the ability to reflect the cumulative glycemic history of the preceding two to three months. HbA1c not only provides a reliable measure of chronic hyperglycemia but also correlates well with the risk of long-term diabetes complications. Elevated HbA1c has also been regarded as an independent risk factor for coronary heart disease and stroke in subjects with or without diabetes. The valuable information provided by a single HbA1c test has rendered it as a reliable biomarker for the diagnosis and prognosis of diabetes. This review highlights the role of HbA1c in diagnosis and prognosis of diabetes patients.