Physical characterization of polycaprolactone scaffolds
Physical characterization of polycaprolactone scaffolds
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DOI：
10.1007/s10856-006-0101-2
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发表时间：
2008-01-01
影响因子：
3.7
通讯作者：
Cortazar, Isabel Castilla
中科院分区：
文献类型：
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作者：
Estelles, Jorge Mas;Vidaurre, Ana;Cortazar, Isabel Castilla
由聚（ε-己内酯）（PCL）在四氢呋喃（THF）中的溶液制备膜和海绵。研究了样品的孔隙率、结晶度和力学性能。在室温下通过蒸发THF产生的膜获得约15%的孔隙率。对于通过在-30 ° C下冷却溶液并随后通过冷冻干燥除去溶剂而获得的海绵，发现多孔结构多得多（50-70%）。用扫描电子显微镜（SEM）观察了样品的孔隙率。在压缩扫描之前和之后，通过量热技术（DSC）研究样品的结晶度。通过压缩试验测定不同样品的机械性能，并将其与对应于本体PCL的机械性能进行比较。压缩扫描不影响样品的结晶度。在不同扫描的结果中观察到的变化归因于孔隙率和结晶度的差异。
Films and sponges were prepared from a solution of Poly(epsilon-caprolactone) (PCL) in tetrahydrofuran (THF). The porosity, crystallinity, and mechanical properties of the samples were studied. Porosity of around 15% was obtained for the films produced by evaporation of THF at room temperature. A much more porous structure (50-70%) was found for the sponges obtained by cooling the solution at -30 degrees C and subsequently eliminating the solvent by freeze drying. The porosity of the samples was also observed by scanning electron microscopy (SEM). The crystallinity of the samples was studied by the calorimetric technique (DSC) before and after the compression scans. The mechanical properties of the different samples were determined by compression test, and were compared to those corresponding to the PCL in bulk. The compression scans did not affect the crystallinity of the samples. The variations observed in the results of the different scans were attributed to the differences in porosities and crystallinity.