Regression, Developmental Trajectory and Associated Problems in Disorders in the Autism Spectrum: The SNAP Study
Regression, Developmental Trajectory and Associated Problems in Disorders in the Autism Spectrum: The SNAP Study
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DOI：
10.1007/s10803-008-0571-9
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发表时间：
2008-11-01
影响因子：
3.9
通讯作者：
Simonoff, Emily
中科院分区：
文献类型：
--
作者：
Baird, Gillian;Charman, Tony;Simonoff, Emily
我们报告了一个由255名9-14岁儿童组成的人群中的回归率和相关发现，这些儿童参加了自闭症谱系障碍（ASD）的患病率研究; 53名狭义自闭症儿童，105名广义ASD儿童和97名非ASD神经发育问题儿童，这些儿童来自56，946名儿童中有特殊教育需求的儿童。据报道，30%的狭义自闭症患者出现语言退化，8%的广义ASD患者出现语言退化，不到3%的非ASD发育问题患者出现语言退化。一小群儿童被确定谁经历了不太明显的挫折。回归与自闭症症状的发生率较高和发展轨迹的偏离有关。退化与癫痫或胃肠道问题无关。
We report rates of regression and associated findings in a population derived group of 255 children aged 9-14 years, participating in a prevalence study of autism spectrum disorders (ASD); 53 with narrowly defined autism, 105 with broader ASD and 97 with non-ASD neurodevelopmental problems, drawn from those with special educational needs within a population of 56,946 children. Language regression was reported in 30% with narrowly defined autism, 8% with broader ASD and less than 3% with developmental problems without ASD. A smaller group of children were identified who underwent a less clear setback. Regression was associated with higher rates of autistic symptoms and a deviation in developmental trajectory. Regression was not associated with epilepsy or gastrointestinal problems.