Adenocarcinoma in Solitary Large Hyperplastic Polyp Diagnosed by Magnifying Colonoscope

Adenocarcinoma in Solitary Large Hyperplastic Polyp Diagnosed by Magnifying Colonoscope
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放大结肠镜诊断孤立性大增生性息肉腺癌

DOI:
10.1007/s10350-004-6434-3
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发表时间:
2002
影响因子:
3.9
通讯作者:
S. Yoshida
S. Yoshida
中科院分区:
医学2区
文献类型:
--
作者:
T. Tonooka;Y. Sano;T. Fujii;S. Kato;T. Yoshino;K. Fu;S. Hironaka;A. Ochiai;S. Yoshida

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:我们报告了一例 78 岁女性增生性息肉癌的病例,该患者在切除前使用放大结肠镜诊断出来。患者出现粪便隐血,并接受全结肠镜检查,结果显示盲肠内有一个 12 毫米的无蒂息肉。当在放大视图中看到时,在息肉的中心有一个明显的不规则形状的凹坑,这与在大多数病变上观察到的小行星型凹坑不同。我们诊断该病变为具有癌成分的增生性息肉。患者接受内镜下粘膜切除术,组织学切片显示增生性息肉内有分化良好的粘膜内腺癌。结肠增生性息肉被认为是良性、非肿瘤性病变。很少有人报道增生性息肉中或伴有增生性息肉的癌,大多数是在切除和组织学检查后确诊的。文献建议对右侧结肠大的孤立性增生性息肉进行精确观察并考虑切除,因为恶性肿瘤的风险很高。放大结肠镜有助于详细观察表面,有助于正确诊断和处理病变。
: We report a case of carcinoma in a hyperplastic polyp in a 78-year-old female that was diagnosed before resection using a magnifying colonoscope. The patient presented with fecal occult blood and underwent total colonoscopy, which revealed a 12-mm sessile polyp in the cecum. When seen in magnified view, an irregularly shaped pit was evident at the center of the polyp that was distinct from the asteroid-type pits observed over most of the lesion. We diagnosed this lesion as a hyperplastic polyp with a carcinoma component. The patient underwent endoscopic mucosal resection, and histologic section revealed a well-differentiated intramucosal adenocarcinoma in the hyperplastic polyp. Hyperplastic polyps of the colon are regarded as benign, nonneoplastic lesions. Few have reported carcinomas in or with hyperplastic polyps, and most of those were diagnosed after resection and histologic investigation. The literature suggests a precise observation and consideration of resection for large solitary hyperplastic polyps in the right side of the colon, because the risk of malignancy is high. Magnifying colonoscopy is helpful for observing the surface in detail and for correctly diagnosing and managing the lesion.
DOI: 10.1136/gut.47.2.251
发表时间: 2000-08-01
期刊: GUT
影响因子: 24.5
作者:
Schlemper, RJ;Riddell, RH;Yamabe, H
通讯作者: Yamabe, H