Cu-catalyzed aerobic oxidative C–CN bond cleavage of benzyl cyanide for the synthesis of primary amides
Cu-catalyzed aerobic oxidative C–CN bond cleavage of benzyl cyanide for the synthesis of primary amides
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DOI：
10.1039/c7ra02207g
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发表时间：
2017-03
期刊：
影响因子：
3.9
通讯作者：
Xiuling Chen;Yanhong Peng;Yan Li;Minghu Wu;Haibing Guo;Jian Wang;Shaofa Sun
中科院分区：
文献类型：
--
作者：
Xiuling Chen;Yanhong Peng;Yan Li;Minghu Wu;Haibing Guo;Jian Wang;Shaofa Sun
An efficient method via copper-catalyzed aerobic oxidative amidation of benzyl cyanide for primary amides is successfully developed. Using readily available NH4Cl as a nitrogen source and Cu/O2 as a catalytic oxidation system offers new opportunities for C–CN bond cleavage and primary amide bond formation.
