Diketopyrrolopyrrole J-aggregates formed by self-organization with DNA
Diketopyrrolopyrrole J-aggregates formed by self-organization with DNA
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与DNA自组织形成二酮吡咯并吡咯J-聚集体
DOI：
10.1002/asia.201402063
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Kazushige Yamana
中科院分区：
文献类型：
--
作者：
Koji Tsuto;Mitsunobu Nakamura;Tadao Takada;Kazushige Yamana
设计并合成了双(2-噻吩基)二酮基吡咯吡咯与两个锌环化合物(ZnCyc-DPP)，以评价锌环与单链DNA中胸腺嘧啶碱基的选择性结合，作为构建DNA上高度有序的多发色团体系的工具。通过UV/Vis滴定、凝胶过滤层析和圆二色谱分析，得到了与寡dTnDNA形成J型DPP聚集体的ZnCyc-DPP。吸附在金电极上的DPP聚集体表现出良好的光电流响应。结果表明，将锌-环-生色团与胸腺嘧啶碱结合在一起是制备具有特定功能的DNA模板多发色体系的有力工具。
Bis(2‐thienyl)diketopyrrolopyrrole with two ZnII‐cyclens (ZnCyc‐DPP) was designed and synthesized to evaluate the selective binding of ZnII‐cyclen with thymine base in single‐strand DNA as a tool for the construction of a highly ordered multichromophore system on DNAs. Through UV/Vis titrations, gel filtration chromatography, and circular dichroism spectroscopy, ZnCyc‐DPP formed J‐type DPP aggregates with oligo‐dTnDNAs. The DPP aggregates absorbed on a gold electrode exhibited good photocurrent responses. The present results show that binding ZnII‐cyclen–chromophore conjugates and thymine bases together is a powerful tool for preparing DNA‐templated multichromophoric systems with specific functions.