Relationships between REM sleep findings and PTSD symptoms during the early aftermath of trauma

Relationships between REM sleep findings and PTSD symptoms during the early aftermath of trauma
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DOI:
10.1002/jts.20246
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发表时间:
2007-10-01
影响因子:
3.3
通讯作者:
Nolan, Bruce
Nolan, Bruce
中科院分区:
医学3区
文献类型:
--
作者:
Mellman, Thomas A.;Pigeon, Wilfred R.;Nolan, Bruce

文献摘要

被引文献

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创伤后应激障碍(PTSD)的实验室睡眠结果被认为与主观抱怨不一致。大多数研究结果与快速眼动(REM)睡眠有关。慢性混淆客观睡眠和PTSD之间的关系。作者报告了创伤后应激障碍症状与创伤后早期客观睡眠测量之间的关系。35例患者在创伤后一个月内接受了Polsomnography和PTSD评估。在2个月时建立创伤后应激障碍状态。REM段持续时间与初始PTSD和失眠严重程度呈负相关,这也与总睡眠时间相关。在REM睡眠期间,一部分病例的相对β频率与创伤后应激障碍和噩梦严重程度呈负相关。这些发现表明,创伤后的主观症状和快速眼动睡眠现象之间存在联系。
Laboratory sleep findings in posttraumatic stress disorder (PTSD) have been characterized as incongruent with subjective complaints. Most findings relate to rapid eye movement (REM) sleep. Chronicity confounds relationships between objective sleep and PTSD. The authors report relationships between PTSD symptoms and objective sleep measures from the early aftermath of trauma. Thirty-five patients received polsomnography and PTSD assessment within a month of traumatic injury. Posttraumatic stress disorder status was establisbed at 2 months. The REM segment duration correlated negatively with initial PTSD and insomnia severity, which also correlated with total sleep time. Relative beta frequency during REM sleep from a subset of cases correlated negatively with PTSD and nightmare severity. These findings suggest a link between subjective symptoms and REM sleep phenomena acutely following trauma.