Response of the alanine/ESR dosimetry system to MV x-rays relative to 60Co radiation
Response of the alanine/ESR dosimetry system to MV x-rays relative to 60Co radiation
复制标题
丙氨酸/ESR 剂量测定系统对 MV X 射线相对于 60Co 辐射的响应
DOI：
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发表时间：
2008
影响因子：
3.5
通讯作者：
F. Renner
中科院分区：
文献类型：
--
作者：
M. Anton;R. Kapsch;M. Krystek;F. Renner
放射治疗剂量学中的相关被测变量是水吸收剂量DW。德国联邦物理技术局（PTB）基于氨基酸丙氨酸的电子自旋共振（ESR），建立了DW的高能光子和电子辐射二级标准。由于校准通常使用60Co辐射进行，而外部放射治疗的很大一部分是使用来自线性加速器的高能X射线进行的，因此确定响应是一个重要的问题。本文中给出的结果是目前最准确的，不确定性分配给8 MV和16 MV的相对响应的顺序为0.3%。使用EGSnrc软件包的Monte Carlo模拟的实验结果进行了比较。在附录中，它演示了如何从重复辐照的平均值及其不确定性，获得了一致的方式使用贝叶斯统计，即使在存在乍一看不一致的数据。重要的是要注意，获得最终结果的公式遵循第一原理，而不是重复使用特别的解决方案或简单的配方，并且适用于所有类型的重复测量。
The measurand relevant in dosimetry for radiation therapy is the absorbed dose to water, DW. The Physikalisch-Technische Bundesanstalt (PTB) has established a secondary standard for DW for high-energy photon and electron radiation based on electron spin resonance (ESR) of the amino acid alanine. Since the calibration is usually performed using 60Co radiation while a huge part of the external radiation therapy is done with high-energy x-rays from linear accelerators, determination of the response is an important issue. The results presented in this paper are the most accurate ones available today with uncertainties assigned to the relative response for 8 MV and 16 MV of the order of 0.3%. The experimental results are compared to Monte Carlo simulations using the EGSnrc software package. In the appendix, it is demonstrated how mean values from repetitive irradiations and their uncertainties are obtained in a consistent way using Bayesian statistics, even in the presence of at first sight inconsistent data. It is important to note that the formulae derived to obtain the final results follow from first principles, without recurring to ad hoc solutions or simple recipes and are valid for all kinds of repetitive measurements.
影响因子：
3.8
作者：
ROGERS, DWO;FADDEGON, BA;MACKIE, TR
通讯作者：
MACKIE, TR