Results of the NIMH collaborative HIV/sexually transmitted disease prevention trial of a community popular opinion leader intervention.
Results of the NIMH collaborative HIV/sexually transmitted disease prevention trial of a community popular opinion leader intervention.
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DOI：
10.1097/qai.0b013e3181d61def
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发表时间：
2010-06
期刊：
影响因子：
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通讯作者：
NIMH Collaborative HIV/STD Prevention Trial Group
中科院分区：
文献类型：
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作者：
NIMH Collaborative HIV/STD Prevention Trial Group
确定社区民意领袖（C-POL）干预场所的社区人群是否比对照场所的人群显示出更大的性风险行为减少和更低的艾滋病毒/性病发病率。2002年至2007年进行了一项5国随机分组试验，在每个国家的20至40个地点招募了队列。场地，在国内匹配的性风险和其他因素，随机分配配对内的C-POL社区干预或艾滋病教育比较。所有参与者都可以获得避孕套，并通过反复深入的性行为访谈，STD/HIV检测和治疗以及HIV/STD风险降低咨询进行评估。在两年内测量性行为改变和HIV/STD发病率。干预和比较条件均显示风险行为患病率下降约33%，并且在国家内部和国家之间、目标人群和场所类型之间具有可比的疾病发病率。社区一级的干预并没有产生更大的行为风险和疾病的发病率降低比比较条件，可能是由于在评估期间所有参与者接受的密集的预防服务。反复、详细地自我审查危险行为的做法，加上艾滋病毒/性病检测、治疗、艾滋病毒风险降低咨询和避孕套的获得，本身就可以大大改变行为和疾病的获得。
To determine whether community populations in Community Popular Opinion Leader (C-POL) intervention venues showed greater reductions in sexual risk practices and lower HIV/STD incidence than those in comparison venues. A 5-country group-randomized trial, conducted from 2002 to 2007, enrolled cohorts from 20 to 40 venues in each country. Venues, matched within country on sexual risk and other factors, were randomly assigned within matched pairs to the C-POL community intervention or an AIDS education comparison. All participants had access to condoms and were assessed with repeated in-depth sexual behavior interviews, STD/HIV testing and treatment, and HIV/STD risk reduction counseling. Sexual behavior change and HIV/STD incidence were measured over two years. Both intervention and comparison conditions showed declines of approximately 33% in risk behavior prevalence and had comparable disease incidence within and across countries, target populations, and types of venues. The community-level intervention did not produce greater behavioral risk and disease incidence reduction than the comparison condition, perhaps due to the intensive prevention services received by all participants during the assessment. Repeated, detailed self-review of risk behavior practices coupled with HIV/STD testing, treatment, HIV risk reduction counseling, and condom access can themselves substantially change behavior and disease acquisition.