Persistent and bilateral choroidal vascular abnormalities in central serous chorioretinopathy
Persistent and bilateral choroidal vascular abnormalities in central serous chorioretinopathy
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DOI：
10.1097/00006982-199911000-00005
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发表时间：
1999-01-01
影响因子：
3.3
通讯作者：
Shimizu, K
中科院分区：
文献类型：
--
作者：
Iida, T;Kishi, S;Shimizu, K
背景：探讨脉络膜血管异常在中心性浆液性脉络膜视网膜病变(CSG)活动期、缓解期及复发中的作用。方法：对104例105眼活动期CSG患者进行吲哚青绿血管造影和荧光素血管造影检查。46例患者随访6~48个月(平均+/-标准差，22.5+/-8.9个月)，取消血管造影(平均+/-标准差，3.5+/-1.5次)。46眼CSC缓解期和6眼复发期均行吲哚青绿血管造影和荧光素血管造影。结果：在活动期CSC中，吲哚青绿血管造影显示脉络膜充盈延迟(71%)，静脉扩张(61%)，局限性脉络膜强荧光(96%)。视网膜渗漏：色素上皮。局灶性脉络膜强荧光出现在患眼的非病变区域(55%)。脉络膜静脉扩张(36%)和脉络膜强荧光(62%)即使在未受影响的对侧眼也可观察到。这些脉络膜异常在整个随访期渗漏停止后的缓解期间持续存在。在6例复发的CSG患者中，新的渗漏发生在持续性脉络膜强荧光区域。6例患者中有1例发生中心性浆液性脉络膜视网膜病变。结论：即使视网膜色素上皮渗漏停止后，双眼仍存在脉络膜血管异常。中心性浆液性脉络膜视网膜病变可在脉络膜血管异常区域复发。
Background: To clarify the role of choroidal Vascular abnormalities in central serous chorioretinopathy (CSG) in active stage, remission, and recurrence.Methods: Indocyanine green angiography and fluorescein angiography were performed in 105 eyes (104 patients) with active CSC. Forty-six patients were followed Lip for 6 to 48 months (mean +/- standard deviation, 22.5 +/- 8.9 months) with repealed angiography (mean +/- standard deviation, 3.5 +/- 1.5 times). Indocyanine green angiography and fluorescein angiography also were performed during remission in all 46 eyes with CSC and during recurrent CSC in 6 eyes. Unaffected fellow eyes underwent angiographic examinations in all patients.Results::ln active CSC, indocyanine green angiography showed a choroidal filling delay (71%), venous dilation (61%), and focal choroidal hyperfluorescence (96%) surrounding. leakage-from he retinal:pigment epithelium. Focal choroidal hyperfluorescence was present in unaffected areas of affected eyes (55%). The choroidal Venous dilation (36%) and choroidal hyperfluorescence (62%) were noted even in unaffected fellow eyes. These choroidal abnormalities persisted during remission after leakage ceased throughout the follow-up period. in the six patients with recurrent CSG, new leakage developed in the areas of persistent choroidal hyperfluorescence. Central serous chorioretinopathy developed in the unaffected fellow eye in one of these six patients.Conclusion: Choroidal vascular abnormalities persist in both eyes even after leakage from the retinal pigment epithelium ceases. Central serous chorioretinopathy may recur in areas of choroidal vascular abnormalities.