Continuous in-the-field measurement of heart rate: Correlates of drug use, craving, stress, and mood in polydrug users.
Continuous in-the-field measurement of heart rate: Correlates of drug use, craving, stress, and mood in polydrug users.
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DOI：
10.1016/j.drugalcdep.2015.03.024
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发表时间：
2015-06-01
影响因子：
4.2
通讯作者：
Preston KL
中科院分区：
文献类型：
--
作者：
Kennedy AP;Epstein DH;Jobes ML;Agage D;Tyburski M;Phillips KA;Ali AA;Bari R;Hossain SM;Hovsepian K;Rahman MM;Ertin E;Kumar S;Preston KL
动态生理监测可以澄清吸毒的前因和后果，并有助于传感器触发的移动干预，自动检测行为风险情况。我们的目标是证明这种监测是可行的并且可以产生有意义的数据。我们使用 AutoSense（一套可将数据无线传输到智能手机的生物传感器）对 40 名接受阿片类药物激动剂维持治疗的多种药物使用者日常生活中的心率 (HR) 进行了长达四个星期的评估。参与者还在电子日记上自我报告药物使用情况、情绪和活动。我们使用多级建模 (SAS Proc Mixed) 将 HR 与自我报告进行比较。 AutoSense 的合规性良好；无线心电图仪的数据率为85.7%。参与者报告使用可卡因时的 HR 高于报告使用海洛因时的 HR (F(2,9) = 250.3，p<.0001），并且作为报告的可卡因剂量的函数也较高 (F(1,8) = 207.7，p<.0001）。当参与者报告渴望海洛因 (F(1,16)=230.9，p<.0001）或可卡因（F(1,14)=157.2，p<.0001）时，HR 高于报告不渴望时的 HR。在随机提示的条目中，参与者报告感到放松、感到快乐或看电视，HR 较低 (p<.05)；而当他们报告感到压力、受到麻烦或行走时，HR 较高。可以从吸毒者日常生活的自然环境中获得高产、高质量的心率数据，所得数据有力地反映了可卡因和海洛因的使用情况以及其他感兴趣的精神和行为事件。
Ambulatory physiological monitoring could clarify antecedents and consequences of drug use and could contribute to a sensor-triggered mobile intervention that automatically detects behaviorally risky situations. Our goal was to show that such monitoring is feasible and can produce meaningful data. We assessed heart rate (HR) with AutoSense, a suite of biosensors that wirelessly transmits data to a smartphone, for up to four weeks in 40 polydrug users in opioid-agonist maintenance as they went about their daily lives. Participants also self-reported drug use, mood, and activities on electronic diaries. We compared HR with self-report using multilevel modeling (SAS Proc Mixed). Compliance with AutoSense was good; the data yield from the wireless electrocardiographs was 85.7%. HR was higher when participants reported cocaine use than when they reported heroin use (F(2,9) = 250.3, p<.0001) and was also higher as a function of the dose of cocaine reported (F(1,8) = 207.7, p<.0001). HR was higher when participants reported craving heroin (F(1,16)=230.9, p<.0001) or cocaine (F(1,14)=157.2, p<.0001) than when they reported of not craving. HR was lower (p<.05) in randomly prompted entries in which participants reported feeling relaxed, feeling happy, or watching TV, and was higher when they reported feeling stressed, being hassled, or walking. High-yield, high-quality heart-rate data can be obtained from drug users in their natural environment as they go about their daily lives, and the resultant data robustly reflect episodes of cocaine and heroin use and other mental and behavioral events of interest.
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影响因子：
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BERNTSON, GG;QUIGLEY, KS;BOYSEN, ST
通讯作者：
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