Fine Structure of the Pars Distalis of the Pituitary Gland in the Female Mink, Mustela vison
Fine Structure of the Pars Distalis of the Pituitary Gland in the Female Mink, Mustela vison
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雌性水貂脑垂体远端的精细结构，Mustela vison
DOI：
10.1111/j.1463-6395.1974.tb00185.x
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发表时间：
1974
期刊：
影响因子：
1.2
通讯作者：
B. Weman
中科院分区：
文献类型：
--
作者：
B. Weman
用电子显微镜观察了成年雌性和未成年雌性水貂的松果体。采用常规方法，包括切除内分泌腺（卵巢和肾上腺），给予放射性同位素、131 I、阻断剂（硫氧嘧啶和甲氧匹隆）和激素（甲状腺素、氢化可的松、促甲状腺激素和促黄体激素释放激素）。五类颗粒细胞区分其超微结构特征和质量的变化，全年和不同的处理。描述了细胞类型并讨论了它们的功能。从传统的电子显微镜研究证明，很难得出任何令人满意的结论，促性腺细胞。需要通过免疫细胞化学和放射免疫测定技术进行进一步研究，以确定假定的促性腺细胞类型是否同时产生FSH和ICSH，或仅产生其中一种激素。
在形态学上鉴定出两种类型的无颗粒细胞。它们的形态相互关系和功能进行了简要的讨论。
Pituitary glands of intact and experimental adult females of mink, Mustela vison, were examined by electron microscopy. Conventional methods involving removal of endocrine glands (ovaries and adrenals), administration of radioactive isotope, 131I, blocking agents (thiouracil and metopirone) and hormones (thyroxine, hydrocortisone, thyrotropin and luteinizing hormone releasing hormones) were employed. Five categories of granular cells were distinguished both by their ultrastructural characteristics and qualitative changes throughout the year and following different treatments. The cell types are described and their functions discussed. From conventional electron microscopical studies it proved difficult to draw any satisfactory conclusions about the gonadotropic cells. Further investigation by means of immunocytochemistry and radioimmunoassay techniques is required to determine, whether the presumptive gonadotropic cell type produces both FSH and ICSH or only one of these hormones.
Morphologically two types of agranular cells were identified. Their morphological inter-relationship and function are discussed briefly.