Synthesis of polyacrylonitrile/polytetrahydropyrimidine (PAN/PTHP) nanofibers with enhanced antibacterial and anti-viral activities for personal protective equipment
Synthesis of polyacrylonitrile/polytetrahydropyrimidine (PAN/PTHP) nanofibers with enhanced antibacterial and anti-viral activities for personal protective equipment
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用于个人防护装备的增强抗菌和抗病毒活性的聚丙烯腈/聚四氢嘧啶（PAN/PTHP）纳米纤维的合成
DOI：
10.1016/j.jhazmat.2021.127602
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发表时间：
2021-11-05
影响因子：
13.6
通讯作者：
Shen, Youqing
中科院分区：
文献类型：
--
作者：
Guo, Shuaibing;Yu, Bing;Shen, Youqing
由细菌和病毒传播引起的新发传染病是全球经济发展和公共卫生的主要负担。目前，大多数个人防护用品的抗菌和抗病毒性能较弱。本文报道的PAN/PTHP纳米纤维为个人防护用品的开发提供了一种新的方法。在本研究中，通过静电纺丝的方法将聚四氟乙烯和聚丙烯腈的混合物制备成具有高效、长效抗菌效果(~gt；99.999%)的聚丙烯腈/聚四氟乙烯纳米纤维。活/死染色和细胞增殖实验表明，制备的PAN/PTHP纳米纤维具有良好的细胞相容性。此外，PAN/PTHP纳米纤维对慢病毒具有明显的破坏作用。基于这些特性，将PAN/PTHP纳米纤维应用于口罩中，可作为口罩的充气杀生层，对空气中的颗粒物具有良好的截留效果。这些引人入胜的材料的成功合成，可能会为新型防护材料的开发提供新的见解。
Emerging infectious diseases caused by the spread of bacteria and viruses are a major burden on global economic development and public health. At present, most personal protective equipment has weak antibacterial and antiviral properties. The PAN/PTHP nanofibers reported in this article provide a new method for the development of personal protective equipment. In this study, a mixture of PTHP and PAN was prepared into PAN/PTHP nanofibers with high-efficiency and long-lasting antibacterial effects (>99.999%) through the electrospinning process. Live/dead staining and cell proliferation experiments showed that the preparation of PAN/PTHP nanofibers has good cell compatibility. In addition, PAN/PTHP nanofibers show obvious destructive effects on lentiviruses. Based on these characteristics, PAN/PTHP nanofibers were applied to facial masks, which can be used as the inflatable biocidal layer of facial masks and have an excellent interception effect on particles in the air. The successful synthesis of these fascinating materials may provide new insights for the development of new protective materials.