EFFECTS OF RELA GENE ON SYNTHESIS OF AMINOACYL-TRANSFER-RNA SYNTHETASES AND OTHER TRANSCRIPTION AND TRANSLATION PROTEINS IN ESCHERICHIA-COLI-B

EFFECTS OF RELA GENE ON SYNTHESIS OF AMINOACYL-TRANSFER-RNA SYNTHETASES AND OTHER TRANSCRIPTION AND TRANSLATION PROTEINS IN ESCHERICHIA-COLI-B
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DOI:
10.1007/bf00268530
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发表时间:
1976-01-01
期刊:
MOLECULAR AND GENERAL GENETICS
影响因子:
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通讯作者:
DENNIS, PP
DENNIS, PP
中科院分区:
其他
文献类型:
--
作者:
BLUMENTHAL, RM;LEMAUX, PG;DENNIS, PP

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部分限制valyl-tRNA氨基酰化对氨基酰-tRNA合成酶、核糖体蛋白和其他翻译和转录蛋白合成的影响在其他同基因的严格(relA+)和松弛(RelA1)衍生物中进行了检验。单个核糖体蛋白的合成,延伸因子[EF]G,以及较小程度的EF-Tu和EF-ts的合成,以及valyl-tRNA合成酶和精氨酰-tRNA合成酶的合成受到严格控制系统的影响。α的合成。和测试版。RNA聚合酶和几种氨基酰-tRNA合成酶的亚基要么不受严格控制系统的影响,要么受到额外的监管限制。
The effects of a partial restriction of valyl-tRNA aminoacylation on the synthesis of aminoacyl-tRNA synthetases, ribosomal proteins and other translation and transcription proteins were examined in otherwise isogenic stringent (relA+) and relaxed (relA1) derivatives of E. coli B. The synthesis of individual ribosomal proteins, elongation factor [EF] G, and to a lesser extent EF-Tu and EF-Ts, and the valyl- and arginyl-tRNA synthetases was subject to the influence of the stringent control system. The synthesis of the .alpha. and .beta. subunits of RNA polymerase and several of the aminoacyl-tRNA synthetases is either not subject to the influence of the stringent control system or is subject to additional regulatory constraints.