Height deficit in early adulthood following substantiated childhood maltreatment: A birth cohort study
Height deficit in early adulthood following substantiated childhood maltreatment: A birth cohort study
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DOI：
10.1016/j.chiabu.2016.12.010
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发表时间：
2017-02-01
影响因子：
4.8
通讯作者：
Najman, Jake Moses
中科院分区：
文献类型：
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作者：
Abajobir, Amanuel Alemu;Kisely, Steve;Najman, Jake Moses
包括童年虐待在内的早期生活压力与儿童和青少年的头围和/或大脑大小减少，认知和学术缺陷有关。然而，人们对童年虐待对身高的影响知之甚少，特别是在成年早期。本研究的目的是检查确诊的儿童期虐待的多重或亚型的病例与控制围产期和家族混杂因素的青年期生长发育迟缓之间的关联。来自Mater医院-大学妊娠研究（MUSP）的2661名年轻人（48.4%为女性）在21年随访时获得了标准化年龄身高评分测量数据，作为身体评估的一部分。经证实的0-14岁儿童虐待案件与MUSP数据集有关。从昆士兰州大学人类伦理审查委员会和Mater医院获得伦理批准。进行多元回归分析，以确定儿童期虐待对年轻成年人身高的影响。在控制了围产期和家庭混杂因素后，儿童期身体或情感虐待和忽视与成年后身高缺陷显著相关。儿童时期的多次虐待事件也与身高不足有关。(C)2016爱思唯尔有限公司版权所有
Early life stress including childhood maltreatment has been associated with reduced head circumference and/or brain size, cognitive, and academic deficits in children and adolescents. However, little is known about the effect of childhood maltreatment on height, especially in early adulthood. This study was designed to examine the association between confirmed cases of multiple or subtypes of childhood maltreatment and stunted growth in young adulthood controlling for perinatal and familial confounding factors. A total of 2661 (48.4% female) young adults from the Mater Hospital-University Study of Pregnancy (MUSP) had data on standardised height-for-age score measurement as part of physical assessment at the 21-year follow-up. Prospectively substantiated cases of childhood maltreatment, 0-14 years of age, were linked to the MUSP dataset. Ethical approval was obtained from the Human Ethics Review Committee of The University of Queensland and the Mater Hospital. Multiple regression analyses were performed to determine the effects of childhood maltreatment on height in young adults. Childhood physical or emotional abuse and neglect were significantly associated with a deficit in height in young adulthood after controlling for perinatal and familial confounders. Multiple incidents of childhood maltreatment also were associated with a deficit in height. (C) 2016 Elsevier Ltd. All rights reserved.