Simultaneous enrichment of bisphenols and polyfluoroalkyl substances by cyclodextrin-fluorinated covalent organic frameworks membrane in food packaging samples
Simultaneous enrichment of bisphenols and polyfluoroalkyl substances by cyclodextrin-fluorinated covalent organic frameworks membrane in food packaging samples
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DOI：
10.1016/j.chroma.2022.462864
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发表时间：
2022-02-03
影响因子：
4.1
通讯作者：
Zhong, Qisheng
中科院分区：
文献类型：
--
作者：
Chen, Yanlong;Lu, Zicheng;Zhong, Qisheng
食品样品中痕量有害物质的高效分离和富集是进行可靠分析的前提。食品样品中大多数不同性质的有害物质共存，难以通过传统吸附剂实现同时提取。本文制备了一种新型的环糊精-氟化共价有机骨架吸附剂（CD-F-COF）。通过分子模拟验证了CD-F-COF识别多氟烷基化合物（PFASs）和双酚（BPs）的机理。CD-F-COF分别对多氟烷基物质（PFASs）和双酚（BPs）表现出较强的亲氟和主客体相互作用。将CD-F-COF涂层膜固定在注射器过滤器上，并与多通道注射泵耦合，以实现高通量样品前处理。结果表明，7种BPs和3种PFASs的检出限分别为0.006 ~ 0.050 ng/g和0.001 ~ 0.008 ng/g。该方法可实现痕量多目标的快速、高通量富集，在样品前处理中具有很大的应用潜力。(c)2022爱思唯尔有限公司版权所有。
Efficient separation and preconcentration of trace harmful substances in food samples is a prerequisite for reliable analysis. Most of harmful substances with different properties coexist in the food samples, which is difficult to achieve simultaneously extraction through traditional adsorbents. In this work, a new adsorbent based on cyclodextrin- fluorinated covalent organic frameworks (CD-F-COF) was prepared. The mechanism of the CD-F-COF recognizing polyfluoroalkyl substances (PFASs) and bisphenols (BPs) were validated by molecular simulation. The CD-F-COF showed strong fluorophilic and host-guest interactions for polyfluoroalkyl substances (PFASs) and bisphenols (BPs), respectively. The CD-F-COF coated membranes were immobilized on the syringe filter and coupled with multi-channel syringe pump to achieve high-throughput sample pretreatment. After that, a sensitive analytical method for the simultaneous enrichment and determination of trace BPs and PFASs was established followed by HPLC-MS/MS. The results indicated that the limits of detection for the seven BPs and three PFASs were in the range of 0.006- 0.050 ng/g and 0.0 01-0.0 08 ng/g. This method has great potential for application in sample preparation as it can fulfill fast and high-throughput for enrichment of trace multiple targets. (c) 2022 Elsevier B.V. All rights reserved.