Use of multiplex PCR to identify Staphylococcus aureus adhesins involved in human hematogenous infections
Use of multiplex PCR to identify Staphylococcus aureus adhesins involved in human hematogenous infections
复制标题
DOI：
10.1128/jcm.41.9.4465-4467.2003
复制
发表时间：
2003-09-01
影响因子：
9.4
通讯作者：
Lina, G
中科院分区：
文献类型：
--
作者：
Tristan, A;Ying, L;Lina, G
我们已经开发了一种多重PCR方法来确定九个粘附素基因在金黄色葡萄球菌分离株中的分布。只有编码骨唾液酸蛋白结合蛋白和纤连蛋白结合蛋白B的基因分别与血源性骨髓炎/关节炎和天然瓣膜心内膜炎显著相关，表明它们参与了血源性组织感染。
We have developed a multiplex PCR procedure to determine the distribution of nine adhesin genes in Staphylococcus aureus isolates. Only genes encoding bone sialloprotein binding protein and fibronectin binding protein B were significantly associated with hematogenous osteomyelitis/arthritis and native-valve endocarditis, respectively, suggesting their involvement in hematogenous tissue infections.