Mifepristone-misoprostol for menstrual regulation in public sector facilities in Bangladesh
Mifepristone-misoprostol for menstrual regulation in public sector facilities in Bangladesh
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DOI：
10.1002/ijgo.12356
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发表时间：
2018-02-01
影响因子：
3.8
通讯作者：
Bracken, Hillary
中科院分区：
文献类型：
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作者：
Alam, Anadil;Lotarevich, Tatyana;Bracken, Hillary
目的了解使用米非司酮和米索前列醇调节月经的情况。方法在一项前瞻性研究中，从2012年11月至2015年6月，在孟加拉国24家政府医疗机构登记了年龄18岁、闭经时间长达9周的妇女。护理人员或女性福利访客提供的月经调节护理最多。参与者服用200 mg米非司酮，24小时后口服800g米索前列醇，并在10-14天后被要求返回诊所进行临床评估和离职面谈。主要结果是在不需要手术干预的情况下成功地排出子宫。完成随访的女性被纳入对主要结果的分析。结果在1744名登记的参与者中，1738人完成了随访。大多数(1674人，96.3%)在不需要手术干预的情况下成功地排出了子宫。一、二级医院的成功率(724/744，97.3%)明显高于专科医院(89/99，89.9%，P
Objective To examine the use of mifepristone and misoprostol for menstrual regulation among Bangladeshi women attending public sector facilities.Methods In a prospective study, women (aged >= 18years) with up to 9weeks of amenorrhea were enrolled at 24 government health facilities in Bangladesh from November 2012 to June 2015. Paramedics or female welfare visitors provided most menstrual regulation care. Participants took 200mg mifepristone followed by 800g buccal misoprostol after 24hours, and were asked to return to the clinic 10-14days later for clinical assessment and an exit interview. The primary outcome was successful evacuation of the uterus without need for surgical intervention. Women who completed follow-up were included in analyses for the primary outcome.Results Among 1744 enrolled participants, 1738 completed follow-up. Most (1674, 96.3%) had a successful uterine evacuation without the need for surgical intervention. A successful outcome was significantly more common in primary (724/744, 97.3%) and secondary facilities (861/895, 96.2%) than in the specialty hospital (89/99, 89.9%; P