Natural microshells of alginate-chitosan : Unexpected stability and permeability
Natural microshells of alginate-chitosan : Unexpected stability and permeability
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DOI：
10.1016/j.polymer.2006.06.038
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发表时间：
2006-08
期刊：
影响因子：
4.6
通讯作者：
Xia Tao;Xue-jun Sun;Jingmei Su;Jianfeng Chen;W. Roa
中科院分区：
文献类型：
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作者：
Xia Tao;Xue-jun Sun;Jingmei Su;Jianfeng Chen;W. Roa
以海藻酸钠（ALG）和壳聚糖（CHI）为壁材，采用静电自组装技术构建了天然可生物降解的海藻酸钠微壳。发现所得ALG-CHI壳在不同的聚（苯乙烯磺酸钠）（PSS）本体浓度（最大检测浓度20.0wt%）下保持完整的球形。与由PSS和聚（烯丙基胺盐酸盐）（PAH）组成的壳在4wt%或大于4wt%的PSS浓度下塌陷或变形相比，ALG-CHI壳显示出更高的稳定性。同时，通过光漂白后荧光恢复（FRAP）直接追踪在PSS溶液中孵育之前和之后的ALG-CHI壳的渗透性。ALG-CHI壳本身的组成被认为是稳定性差异的原因。
We utilized alginate sodium (ALG) and chitosan (CHI) as wall components to construct a natural and biodegradable polyelectrolyte microshell by the electrostatic self-assembly technique. The resultant ALG–CHI shells were found to maintain intact spherical shape in different poly(styrenesulfonate sodium) (PSS) bulk concentrations (maximal detection concentration 20.0wt%). Compared with the shells composed of PSS and poly(allylamine hydrochloride) (PAH) that collapse or deform at a 4wt% or more than 4wt% PSS concentration, the ALG–CHI shells display higher stability. Meanwhile, the permeability of the ALG–CHI shells prior to and after incubation in PSS solutions was directly traced by the fluorescence recovery after photobleaching (FRAP). The composition of the ALG–CHI shells themselves is thought to be responsible for the differences in the stability.