Quasi-steady state assumptions for non-isolated enzyme-catalysed reactions
Quasi-steady state assumptions for non-isolated enzyme-catalysed reactions
复制标题
DOI：
10.1007/s00285-003-0225-7
复制
发表时间：
2004
影响因子：
1.9
通讯作者：
I. Stoleriu;F. A. Davidson;J. Liu
中科院分区：
文献类型：
--
作者：
I. Stoleriu;F. A. Davidson;J. Liu
研究了酶催化生化反应Michaelis-Menten型动力学数学公式的性质和有效性。几乎所有以前的工作都集中在孤立的反应上，即那些没有输入或其他环境影响的反应。在本文中，我们研究了底物输入对这一公式的影响，特别是对准稳态假设的性质和有效性的影响。
The nature and validity of the mathematical formulation of Michaelis-Menten type kinetics for enzyme-catalysed biochemical reactions is studied. Almost all previous work has concentrated on isolated reactions, i.e. those without input or other environmental influences. In this paper, we investigate the effects of substrate input on this formulation, in particular, on the nature and validity of thequasi-steady state assumptions.