Acetaminophen influences social and economic trust
Acetaminophen influences social and economic trust
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DOI：
10.1038/s41598-019-40093-9
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发表时间：
2019-03-11
影响因子：
4.6
通讯作者：
Way, Baldwin M.
中科院分区：
文献类型：
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作者：
Roberts, Ian D.;Krajbich, Ian;Way, Baldwin M.
长期以来，扑热息痛一直被认为可以选择性地缓解身体疼痛，但最近的研究开始揭示其更广泛的心理影响。在这项工作的基础上，我们通过一项全国性的调查和五项实验室实验，发现了对乙酰氨基酚影响基本社会信任过程的提示性证据。在国家社区样本(MIDUS II)中，扑热息痛的使用与邻里信任和社会融合感呈负相关。在一系列实验室实验中(N=767)，扑热息痛降低了信任游戏中自我产生的预期对投资的影响。当我们操纵信托游戏投资者的预期时，对乙酰氨基酚增加了投资，而不考虑预期。这些结果首次证明非处方药可以影响与信任相关的行为。总体而言，这些发现描绘了一幅情景因素如何影响药物效果的复杂图景。
Acetaminophen has long been assumed to selectively alleviate physical pain, but recent research has started to reveal its broader psychological effects. Building on this work, we find suggestive evidence that acetaminophen affects the basic social process of trust across a national survey and five lab experiments. In a national community sample (MIDUS II), acetaminophen usage was negatively associated with neighborhood trust and feelings of social integration. In a series of lab experiments (N = 767), acetaminophen reduced the influence of self-generated expectations on investments in a trust game. When we manipulated trust game investor expectations, acetaminophen increased investments regardless of expectations. These results provide the first demonstration that an over-the-counter drug can impact trust-related behavior. Overall, the findings paint a complex picture of how situational factors may influence drug effects.