Results and lessons learned from a small medical abortion clinical study in Turkey
Results and lessons learned from a small medical abortion clinical study in Turkey
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DOI：
10.1016/j.contraception.2004.05.005
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发表时间：
2004-11-01
期刊：
影响因子：
2.9
通讯作者：
Winikoff, B
中科院分区：
文献类型：
--
作者：
Akin, A;Blum, J;Winikoff, B
这篇文章介绍了一项小型的介绍性临床研究的结果，该研究为土耳其妇女提供了一种简化的药物流产方案。从2000年7月至2001年3月，从五个地点共招募了208名妇女。所有符合条件的女性在诊所给予200 mg米非司酮口服，2天后在家或在诊所口服米索前列醇400杯。84.1%的总体成功率低于之前对该方案的研究，被诊断为不完全流产的妇女比例高得令人惊讶(9.1%)。尽管失败率高于预期，但女性表示了高度的满意度。在这项研究中面临着几个挑战，为如何将药物堕胎引入最有可能成功的新环境提供了有价值的见解。(C)2004 Elsevier Inc.保留所有权利。
This article presents results from a small, introductory clinical study offering a simplified regimen medical abortion to women in Turkey. A total of 208 women from five sites were recruited from July 2000 through March 2001. All eligible consenting women were given 200mg oral mifepristone at the clinic followed by 400 mug oral misoprostol 2 days later either at home or at the clinic. The overall success rate of 84.1% is lower than in previous studies of this regimen, and a surprisingly high proportion of women (9.1%) were diagnosed with incomplete abortion. In spite of the higher than expected failure rate, women expressed a high degree of satisfaction. Several challenges were faced during this study, providing valuable insights about ways to introduce medical abortion into new settings with the best chances for success. (C) 2004 Elsevier Inc. All rights reserved.