Probiotic properties of Lactobacillus plantarum CECT 7315 and CECT 7316 isolated from faeces of healthy children
Probiotic properties of Lactobacillus plantarum CECT 7315 and CECT 7316 isolated from faeces of healthy children
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DOI：
10.1111/j.1472-765x.2011.03199.x
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发表时间：
2012-03-01
影响因子：
2.4
通讯作者：
Cune, J.
中科院分区：
文献类型：
--
作者：
Bosch, M.;Rodriguez, M.;Cune, J.
目的：并非所有的乳酸菌都具有为宿主提供健康益处的能力。因此，有必要筛选和表征众多菌株以获得理想的益生菌。本文对两株植物乳杆菌（Lactobacillus plantarum）CECT 7315和CECT 7316进行了分离鉴定。植物菌株这两种菌株均显示出在胃肠道条件下的高存活能力和粘附肠上皮细胞的能力，以及对多种肠道病原体的强抑制活性和诱导抗炎细胞因子IL-10产生的能力。植物乳杆菌CECT 7315/CECT 7316由于其潜在的益生菌特性，可能是临床试验中测试的优秀候选者，旨在证明对人类健康的有益作用。益生菌是活的微生物，为宿主带来健康益处。然而，并非所有的乳酸菌都具有为宿主提供健康益处的能力。在这项研究中，两个乳糖。分离并表征了植物益生菌菌株（CECT 7315和CECT 7316），以证明它们作为潜在益生菌菌株的优异品质。
Aims: Not all lactic acid bacteria possess the ability to confer health benefits for the host. Thus, it becomes necessary to screen and characterize numerous strains to obtain ideal probiotics. Here, two Lactobacillus plantarum strains (CECT 7315 and CECT 7316) were isolated and characterized.Methods and Results: In vitro and in vivo tests were carried out for demonstrating the abilities as probiotics of CECT 7315/CECT 7316 Lact. plantarum strains. Both strains showed high ability to survive at gastro-intestinal tract conditions and to adhere to intestinal epithelial cells, as well as great inhibitory activity against a wide range of enteropathogens and ability to induce the production of anti-inflammatory cytokine IL-10.Conclusions: Lactobacillus plantarum CECT 7315/CECT 7316 because of their potential probiotic properties could be excellent candidates for being tested in clinical trials aimed to demonstrate beneficial effects on human health.Significance and Impact of the Study: Probiotics are live micro-organisms that confer a health benefit for the host. However, not all the lactic acid bacteria possess the ability to confer health benefits for the host. In this study, two Lact. plantarum strains (CECT 7315 and CECT 7316) were isolated and characterized to demonstrate their excellent qualities as potential probiotic strains.