Cerebellar activation in opsoclonus - An fMRI study
Cerebellar activation in opsoclonus - An fMRI study
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DOI：
10.1212/01.wnl.0000073271.66866.51
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发表时间：
2003-08-12
期刊：
影响因子：
9.9
通讯作者：
Binkofski, F
中科院分区：
文献类型：
--
作者：
Helmchen, C;Rambold, H;Binkofski, F
视阵挛是小脑疾病还是脑干疾病尚有争议。两名患者的眼阵挛大部分消失的眼睛关闭进行功能磁共振成像。对这两种状态的比较显示，小脑深部核团的双侧激活超过了作者在健康受试者中发现的水平，而不是小脑和脑干的激活。这些结果支持了顶核在视阵挛中的重要作用。
It is controversial whether opsoclonus is a cerebellar or brainstem disorder. Two patients whose opsoclonus largely disappeared on eye closure underwent fMRI. A comparison of these two states revealed neither vermal nor brainstem activation but rather a bilateral activation in the deep cerebellar nuclei in excess of what the authors found in healthy subjects. The results support a crucial role of the fastigial nucleus in opsoclonus.