CHORIORETINAL LESIONS IN CHRONIC GRANULOMATOUS-DISEASE OF CHILDHOOD - CLINICOPATHOLOGIC CORRELATIONS
CHORIORETINAL LESIONS IN CHRONIC GRANULOMATOUS-DISEASE OF CHILDHOOD - CLINICOPATHOLOGIC CORRELATIONS
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DOI：
10.1097/00006982-198808040-00009
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发表时间：
1988-01-01
影响因子：
3.3
通讯作者：
JACOBS, G
中科院分区：
文献类型：
--
作者：
GROSSNIKLAUS, HE;FRANK, KE;JACOBS, G
作者检查了一只从儿童慢性肉芽肿性疾病和临床明显脉络膜视网膜疤痕患者死后获得的眼睛。组织学检查发现许多脉络膜视网膜瘢痕与相关的视网膜色素上皮细胞的变化和胶质细胞增生。细菌和真菌的特殊染色为阴性。其他发现是在患者的脾、肝、淋巴结、骨髓、肺、肾、胸腺、脉络膜和视网膜中发现散在的含色素巨噬细胞。色素巨噬细胞的意义尚不清楚，但它们可能代表了对感染因子的失败巨噬细胞反应。视网膜8：270-274，1988年
The authors examined an eye obtained postmortem from a patient with chronic granulomatous disease of childhood and clinically apparent chorioretinal scars. Histologic examination disclosed numerous chorioretinal scars with associated retinal pigment epithelial changes and glial proliferation. Special stains for bacteria and fungi were negative. Additional findings were scattered pigment-containing macrophages found in the patient's spleen, liver, lymph nodes, bone marrow, lungs, kidney, thymus, choroid, and retina. The significance of the pigmented macrophages is unknown, however they may represent an abortive macrophage response to infectious agents. RETINA 8: 270-274, 1988