Comorbidity of Headache and Depression After Mild Traumatic Brain Injury
Comorbidity of Headache and Depression After Mild Traumatic Brain Injury
复制标题
DOI：
10.1111/head.12762
复制
发表时间：
2016-02-01
期刊：
影响因子：
5
通讯作者：
Hoffman, Jeanne M.
中科院分区：
文献类型：
--
作者：
Lucas, Sylvia;Smith, Brendon M.;Hoffman, Jeanne M.
目的研究轻度颅脑损伤(MTBI)患者随时间变化的头痛和抑郁症状。本研究评估了颅脑损伤后早期和伤后1年头痛和抑郁的发生率以及两者之间的关系。背景头痛是最常见的躯体症状，抑郁是颅脑损伤后最常见的精神诊断之一，无论严重程度如何。头痛和抑郁已被发现是mTBI后预后不良的两个独立因素，但关于这两种情况在损伤后的并存情况的研究似乎很少。方法/设计纵向调查设计212名mTBI患者，他们在一级创伤中心接受观察或其他系统损伤。抑郁症是基于患者健康问卷-9上的10分。结果基线时头痛和抑郁的患病率分别为%(135/212)和15%(31/212)。1岁时头痛和抑郁的患病率分别为68%(127/187)和27%(50/187)。头痛和抑郁的并存从基线时的11%(23/212)增加到1年时的25%(46/187)。1年后头痛患者抑郁的危险比为5.43(95%可信区间为2.05~14.40)，与非头痛患者相比差异有统计学意义(P
ObjectiveTo examine headache and depression over time in individuals who sustained mild traumatic brain injury (mTBI). Prevalence of headache and depression early after mTBI and at 1 year postinjury as well as the relationship between the two are evaluated.BackgroundHeadache is the most common physical symptom and depression is among the most common psychiatric diagnosis after traumatic brain injury regardless of severity. Headache and depression have been found to be two independent factors related to poor outcome after mTBI, yet there appears to be a paucity of research exploring the comorbidity of these two conditions after injury.Method/DesignLongitudinal survey design over 1 year of 212 participants with mTBI who were admitted to a Level 1 trauma center for observation or other system injuries. Depression was based on a score 10 on the Patient Health Questionnaire-9. Headache was based on participant report of new or worse-than-preinjury headache since hospitalization (baseline) or within the previous 3 months at 1 year postinjury.ResultsThe prevalence of headache and depression at baseline was 64% (135/212) and 15% (31/212), respectively. The prevalence of headache and depression at 1 year was 68% (127/187) and 27% (50/187), respectively. The co-occurrence of headache and depression increased from 11% (23/212) at baseline to 25% (46/187) at 1 year. At 1 year, the risk ratio of individuals who had headache to be depressed was 5.43 (95% CI 2.05-14.40) compared to those without headache (P