Identification of peptide features in precursor spectra using Hardklör and Krönik.
Identification of peptide features in precursor spectra using Hardklör and Krönik.
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使用 Hardklör 和 Krönik 鉴定前体光谱中的肽特征。
DOI：
10.1002/0471250953.bi1318s37
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发表时间：
2012
影响因子：
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通讯作者：
Moritz,RobertL
中科院分区：
文献类型：
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作者：
Hoopmann,MichaelR;MacCoss,MichaelJ;Moritz,RobertL
Hardklör和Krönik是用于高分辨率质谱特征检测和数据简化的软件工具。Hardklör用于将肽同位素分布还原为单一的单同位素质量和电荷状态，并且可以对重叠的肽同位素分布进行反卷积。Krönik过滤、验证并总结了从液相色谱-质谱（LC - MS）中获得的数据中通过Hardklör识别的肽特征。这两个软件工具都包含一个简单的用户界面，几乎可以在任何台式计算机上运行。这些工具可以从http://proteome.gs.washington.edu/software/hardklor.Curr免费获得。Protoc。Bioinform 37:13.18.1 13.18.13应承担的。©2012 by John Wiley & Sons, Inc。
Hardklör and Krönik are software tools for feature detection and data reduction of high‐resolution mass spectra. Hardklör is used to reduce peptide isotope distributions to a single monoisotopic mass and charge state, and can deconvolve overlapping peptide isotope distributions. Krönik filters, validates, and summarizes peptide features identified with Hardklör from data obtained during liquid chromatography mass spectrometry (LC‐MS). Both software tools contain a simple user interface and can be run from nearly any desktop computer. These tools are freely available from http://proteome.gs.washington.edu/software/hardklor.Curr. Protoc. Bioinform. 37:13.18.1‐13.18.13. © 2012 by John Wiley & Sons, Inc.