Memory Impairments Following Lesions to the Mammillary Region of the Rat
Memory Impairments Following Lesions to the Mammillary Region of the Rat
复制标题
大鼠乳头区域损伤后的记忆障碍
DOI：
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发表时间：
1993
影响因子：
3.4
通讯作者：
M. Petrides
中科院分区：
文献类型：
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作者：
V. Sziklas;M. Petrides
研究了乳头区对学习和记忆的贡献。研究表明，该区域的病变损害了需要记忆空间信息的任务的性能，但赤字取决于该区域内的损伤量和任务的难度。这种病变对可比空间和非空间记忆任务的表现的影响存在分离。与在空间记忆任务中观察到的缺陷相反，在乳头区广泛损伤后，复杂非空间记忆任务的获得和保持并未受损。这样的病变也没有损害性能的条件性味觉厌恶任务。这些实验表明，乳头区可能选择性地参与空间学习和记忆。
The contribution of the mammillary region to learning and memory was investigated. It was demonstrated that lesions of this region impair performance on tasks that require memory for spatial information but that the deficit depends both on the amount of damage within the region and the difficulty of the task. A dissociation in the effect of such lesions on performance of comparable spatial and non‐spatial memory tasks was shown. In contrast to the deficits observed on spatial memory tasks, the acquisition and retention of a complex non‐spatial memory task was not impaired after extensive damage to the mammillary region. Such lesions also did not impair performance in a conditioned taste aversion task. These experiments suggest that the mammillary region may be selectively involved in spatial learning and memory.