Autoimmune encephalitis: a review of diagnosis and treatment

Autoimmune encephalitis: a review of diagnosis and treatment
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DOI:
10.1590/0004-282x20170176
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发表时间:
2018-01-01
影响因子:
1.4
通讯作者:
Hoftberger, Romana
Hoftberger, Romana
中科院分区:
医学4区
文献类型:
--
作者:
Dutra, Lívia Almeida;Abrantes, Fabiano;Hoftberger, Romana

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自身免疫性脑炎(AIE)是非感染性脑炎最常见的病因之一。它可以由肿瘤,感染触发,也可能是隐源性的。神经系统表现可以是急性或亚急性,通常在六周内发展。有多种临床表现,包括行为和精神症状,自主神经紊乱,运动障碍和癫痫发作。我们回顾了AIE的常见形式,并讨论其诊断方法和治疗。
Autoimmune encephalitis (AIE) is one of the most common causes of noninfectious encephalitis. It can be triggered by tumors, infections, or it may be cryptogenic. The neurological manifestations can be either acute or subacute and usually develop within six weeks. There are a variety of clinical manifestations including behavioral and psychiatric symptoms, autonomic disturbances, movement disorders, and seizures. We reviewed common forms of AIE and discuss their diagnostic approach and treatment.