HISTOPATHOLOGY AND PROGNOSIS OF MALIGNANT COLORECTAL POLYPS TREATED BY ENDOSCOPIC POLYPECTOMY
HISTOPATHOLOGY AND PROGNOSIS OF MALIGNANT COLORECTAL POLYPS TREATED BY ENDOSCOPIC POLYPECTOMY
复制标题
DOI：
10.1136/gut.25.5.437
复制
发表时间：
1984-01-01
期刊：
影响因子：
24.5
通讯作者：
WILLIAMS, CB
中科院分区：
文献类型：
--
作者：
MORSON, BC;WHITEWAY, JE;WILLIAMS, CB
本文介绍了 60 例内镜息肉切除术中恶性息肉的组织病理学特征和治疗结果。对患者进行至少 5 年的随访。 46 例患者仅接受息肉切除术，因为判断局部切除已完全且浸润性癌分化良好或中度良好。其中 37 名患者在 5 年后仍存活且状况良好；其余 9 人在 4 年后因其他原因死亡。这些病例中没有任何复发的证据。 14 名患者随后接受了大手术切除； 2例息肉切除部位发现肿瘤残留，但未累及区域淋巴结。尽管手术标本中没有肿瘤，但该组中只有 1 名患有高级别肿瘤的患者出现转移。只要严格应用实验室检查技术和组织病理学标准，仅通过息肉切除术就可以成功治疗恶性息肉。
The histopathological features and results of treatment of malignant polyps removed by endoscopic polypectomy from 60 patients are presented. The patients were followed for a minimum of 5 yr. Forty-six patients were treated by polypectomy alone as local excision was judged complete and the invasive carcinoma was well or moderately well differentiated. Thirty-seven of these patients are alive and well after 5 yr; the remaining 9 have died of other causes up to 4 yr later. There was no evidence of recurrence in any of these cases. Fourteen patients underwent a subsequent major surgical resection; residual tumor was found at the site of polypectomy in 2 cases, but regional lymph nodes were not involved. Only 1 patient from this group with a high grade tumor developed metastases although the operative specimen was free of tumor. Malignant polyps can be successfully treated by polypectomy alone provided both the laboratory techniques of examination and the histopathological criteria are strictly applied.