DEFECT IN CYCLIC-AMP PHOSPHODIESTERASE DUE TO THE DUNCE MUTATION OF LEARNING IN DROSOPHILA-MELANOGASTER
DEFECT IN CYCLIC-AMP PHOSPHODIESTERASE DUE TO THE DUNCE MUTATION OF LEARNING IN DROSOPHILA-MELANOGASTER
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DOI：
10.1038/289079a0
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发表时间：
1981-01-01
期刊：
影响因子：
64.8
通讯作者：
KIGER, JA
中科院分区：
文献类型：
--
作者：
BYERS, D;DAVIS, RL;KIGER, JA
可以使用基因突变体来探索 cAMP 参与学习机制的可能性。为此，黑腹果蝇是合适的，因为它具有良好的遗传特征。对嗅觉学习和 cAMP 代谢突变以及导致女性不孕的突变的独立搜索均导致了相同的基因。sbd.the dunce 基因。正常的 dunce 基因可能指定 cAMP 磷酸二酯酶。
The possibility that cAMP participates in learning mechanisms can be explored using genetic mutants. For this purpose, D. melanogaster is suitable as it is genetically well characterized. Independent searches for mutations of olfactory learning and of cAMP metabolism, and for mutations causing female infertility have each led to the same gene.sbd.the dunce gene. The normal dunce gene may specify cAMP phosphodiesterase.