ALCOHOL INTAKE AND BONE-MINERAL DENSITY IN ELDERLY MEN AND WOMEN - THE FRAMINGHAM-STUDY
ALCOHOL INTAKE AND BONE-MINERAL DENSITY IN ELDERLY MEN AND WOMEN - THE FRAMINGHAM-STUDY
复制标题
DOI：
10.1093/oxfordjournals.aje.a117664
复制
发表时间：
1995-09-01
影响因子：
5
通讯作者：
KIEL, DP
中科院分区：
文献类型：
--
作者：
FELSON, DT;ZHANG, YQ;KIEL, DP
饮酒对骨骼有多方面的影响，而酗酒的男性有很高的骨质疏松性骨折的风险，这项研究的目的是评估饮酒与老年人骨密度之间的关系，作者在两年一度的第20次考试(1988-1989)中评估了1,154名弗雷明翰心脏研究队列成员。受试者的年龄从68岁到96岁不等。骨密度在桡骨(超骨和骨干)以及股骨和脊柱近端进行评估，酒精消耗量从检查12(1967-1969)到检查20，每两年评估一次，平均。在调整了年龄、体重、身高、吸烟，以及女性绝经年龄和雌激素使用年限后，研究了酒精摄入量与骨密度的相关性。每周至少饮酒7盎司(206.99毫升)的女性在大多数部位的骨密度(4.2%-13.0%范围，所有部位的平均差异为7.7%)高于最轻摄入类别的女性(
Alcohol consumption has multiple effects on bone, and alcoholic men have a high risk of osteoporotic fracture, The objective of this study was to assess the association between alcohol consumption and bone mineral density in elders, The authors evaluated 1,154 members of the Framingham Heart Study Cohort at biennial examination 20 (1988-1989). Subjects ranged in age from 68 to 96 years. Bone density was assessed at the radius (ultradistal and shaft) and at the proximal femur and spine, Alcohol consumption, assessed every 2 years from examination 12 (1967-1969) through examination 20, was averaged. The association of alcohol intake with bone density was examined after adjustment for age, weight, height, smoking, and, in women, age at menopause and years of estrogen use. Women who drank at least 7 oz (206.99 ml)/week of alcohol had higher bone densities at most sites (4.2-13.0% range with 7.7% average differences across all sites) than women in the lightest category of intake (